Guiomar 2024 conducted the first annual seroprevalence survey from 2014 to 2019 of infection- and vaccination-induced protective Abs against influenza A(H1N1)pdm09, A(H3N2), B/Victoria, and B/Yamagata in Portugal to assess the seroprevalence of protective Abs against influenza virus and to evaluate the correlation of seroprevalence measured in summer with the influenza like-illness (ILI) rate in the following influenza season. Researchers found significant differences in the seroprevalence of protective Abs against influenza in the population, according to age, vaccination status, and geographic region, providing insight into the relationship between the seroprevalence of protective Abs against influenza and the reduction of the ILI incidence rate in the next season.
Milestone
1.1.d
Seroprevalence studies
In progress
High priority
Develop a comprehensive landscape of population-based serosurveillance studies in different age groups and geographic regions to better understand the relationship between population immunity to seasonal influenza viruses and antigenic drift, which is needed to determine how serosurveillance data can be used to improve decisions regarding vaccine strain selection for seasonal influenza vaccine production.