University of Minnesota
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Animal Models and the Controlled Human Influenza Virus Infection Model (CHIVIM)

Milestones relevant to animal models and the CHIVIM address strategies for optimizing animal models for use in influenza vaccine research and for refining the CHIVIM to maximize its effectiveness. View more details in the Influenza Vaccines Research & Development Roadmap.

Milestones completed
3
Milestones in progress
8
Milestones not started
0
Goals
Strategic goal
5.1

Optimized animal models

Optimize animal models for influenza vaccine research.

Milestones
5.1.a
Ongoing

Resource sharing

5.1.b
High priority
Ongoing

Reagents, viral stocks, and assays

5.1.c

Transmission studies

5.1.d

Pre-exposure models

5.1.e
High priority

Ferret model refinement

5.1.f
High priority

Predictive value

5.1.g
High priority

Novel models

5.1.h

Ferret MHC epitopes

Strategic goal
5.2

CHIVIM refinements

Address steps needed to further develop and refine the CHIVIM.

Milestones
5.2.a
High priority

Guidance for use

5.2.b
High priority

Virus strain availability

5.2.c

Protocols for multi-center studies