The NIAID supported EMIT-2 study has developed and implemented analytical models of influenza transmission to optimize a hotel quarantine facility for conducting CHIVIMs that mitigates the risk of unwanted transmission outside of the experimental environment.
Lane 2024 summarized discussions and outcomes from NIAID’s workshop (CHIVIM studies: current status and future directions for innovation, Nov. 13-14, 2023), which addresses issues regarding the feasibility of conducting transmission studies using CHIVIM studies.
Belser 2023 analyzed practical obstacles and limitations on performing virus transmission studies in laboratory environments, the additional challenges posed by conducting these experiments concurrent with in vivo experimentation, and how continued investment in this work will provide greater understanding of the role aerosols play in viral transmission.