University of Minnesota
https://twin-cities.umn.edu/
612-625-5000

Vaccinology for Broadly Protective/Universal Influenza Vaccines

Milestones for broadly protective or universal vaccinology focus on generating and assessing new constructs for broadly protective and durable influenza vaccines and ensuring that promising vaccine candidates move through the vaccine development pipeline.

Milestones completed
3
Milestones in progress
7
Milestones not started
1
Goals
Strategic goal
4.1

Design and analysis

Identify the most promising broadly protective or universal influenza vaccine candidates that elicit durable protection against influenza viruses in preclinical studies, with a focus on targeting conserved regions of the virus.

Milestones
4.1.a

Preferred product characteristics

4.1.b

Landscape analysis

4.1.c
High priority

New antigen design

4.1.d
High priority

Review of novel platforms

4.1.e
High priority

Review of preclinical candidates

Strategic goal
4.2

Clinical evaluation

Evaluate the most promising broadly protective or universal influenza vaccine candidates, using at least several different platforms, in clinical trials.

Milestones
4.2.a

Use cases

4.2.b
High priority

Defined clinical endpoints

4.2.c
High priority

Early clinical evaluation

4.2.d
High priority

Correlates of protection

4.2.e
High priority

Advanced clinical evaluation

4.2.f
High priority

Phase 3 efficacy trials