Belser 2022 conducted a cross-laboratory standardization exercise for influenza risk assessment studies in ferrets to improve the interpretation of transmission data generated during risk assessment activities.
Milestone
5.1.c
Transmission studies
In progress
Harmonize best practices for conducting influenza virus transmission studies in animals such as hamsters and guinea pigs, as was done in ferrets, to include naive and infected or vaccinated animals.
Progress Highlights
CEPI established a preclinical models network for testing vaccines against priority pathogens, which could serve as a guide in influenza vaccine development, which may support the development of models other than ferrets and the resolution of regulatory issues involving preclinical data requirements.